愛媛大学沿岸環境科学研究センター　化学汚染・毒性解析部門：環境毒性学(岩田)研究室
Japanese
基盤研究(S)のページ
研究の概要 | 研究業績 2012年度 2011年度 2010年度2009年度

著書

  1. 岩田久人 (2010)　:
    環境毒性学　3.6 バイオマーカー,
    朝倉書店, 137-147.
  2. 岩田久人 (2011)　:
    環境毒性学　７　環境毒性学の未来,
    朝倉書店
  3. Ishibashi, H., Kim, E. Y., Tanabe, S. and Iwata, H. (2010):
    Molecular characterization of peroxisome proliferator-activated receptor isoforms from the Baikal seal (Pusasibirica),
    Interdisciplinary Studies on Environmental Chemistry Vol. 4, Environmental Specimen Bank: Exploring Possibility of Setting-up ESBs in Developing Countries,
    TERRAPUB, 133-139.
  4. Hirano, M., Ishibashi, H., Kim, E. Y., Arizono, K. and Iwata, H. (2010):
    Development of an in vitro reporter gene assay for screening the ecdysone receptor agonists in mysid crustacean,
    Interdisciplinary Studies on Environmental Chemistry Vol. 4, Environmental Specimen Bank: Exploring Possibility of Setting-up ESBs in Developing Countries,
    TERRAPUB, 141-147.
  5. Iida, M., Kim, E. Y., Murakami, Y., Shima, Y. and Iwata, H. (2010):
    Toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on peripheral nervous system of developing red seabream (Pagrus major) embryos,
    Interdisciplinary Studies on Environmental Chemistry Vol. 4, Environmental Specimen Bank: Exploring Possibility of Setting-up ESBs in Developing Countries,
    TERRAPUB, 149-154.
  6. Suzuki, K. T. and Iwata, H. (2010):
    Cytochrome P450 family 1 genes in Xenopustropicalis,
    Interdisciplinary Studies on Environmental Chemistry Vol. 4, Environmental Specimen Bank: Exploring Possibility of Setting-up ESBs in Developing Countries,
    TERRAPUB, 155-160.
  7. Agusa, T., Iwata, H., Fujihara, J., Kunito, T., Takeshita, H., Minh, T. B., Trang, P. T. K., Viet, P. H. and Tanabe, S. (2010):
    Interindividual variation in arsenic metabolism in a Vietnamese population: association with 17 single nucleotide polymorphisms in AS3MT,
    Interdisciplinary Studies on Environmental Chemistry vol. 3, Biological Responses to Contaminants:
    from Molecular to Community Level,
    TERRAPUB,113-119.
  8. Iwata, H. and Kim, E.Y. (2010):
    Risk assessment of dioxins in wild birds by the combination of contamination level and species-specific response of aryl hydrocarbon receptor,
    Interdisciplinary Studies on Environmental Chemistry vol. 3, Biological Responses to Contaminants: from Molecular to Community Level,
    TERRAPUB,105-112.
  9. Agusa, T., Fujihara, J., Takeshita, H., Tanabe, S., Iwata, H., Kunito, T., Minh, T. B., Trang, P. T. K. and Viet, P. H. (2010): Methylation of inorganic arsenic and genetic polymorphisms in arsenic (+III oxidation state) methyltransferase in a Vietnamese population,
    Arsenic in Geosphere and Human Diseases,
    CRC Press,329-331.
  10. 能勢眞人 (2010):
    リウマチ病学テキスト,
    診断と治癒社,242-246.

原著論文

  1. Kim, E. Y., Suda, T., Tanabe, S., Batoev, V. B., Petrov, E. A. and Iwata, H. (2011):
    Evaluation of relative potencies for in vitro transactivation of the Baikal seal aryl hydrocarbon receptor by dioxin-like compounds,
    Environmental Science ＆ Technology, 45(4), 1652-1658.
  2. Lee, J. S., Kim, E. Y., Nomaru, K. and Iwata, H. (2011):
    Molecular and functional characterization of aryl hydrocarbon receptor repressor from the chicken (Gallus gallus): interspecies similarities and differences,
    Toxicological Sciences, 119(2), 319-334.
  3. Agusa, T., Takagi, K., Miller, T. W., Kubota, R., Anan, Y., Iwata, H. and Tanabe, S. (2011):
    Intake and excretion of arsenicals in green (Cheloniamydas) and hawksbill turtles (Eretmochelysimbricata),
    Environmental Chemistry, 8(1), 19-29.
  4. Fujihara, J., Hasegawa, M., Kanai, R., Agusa, T., Iwata, H., Tanabe, S., Yasuda, T., Yamaguchi, S. and Takeshita, H.(2011):
    8-Hydroxy-2'-deoxyguanosine and arsenic compounds in urine and serum of a 4-year-old child suffering from acute promyelocytic leukemia during treatment with arsenic trioxide,
    Forensic Toxicology, 29(1), 65-68.
  5. Watanabe, M.X., Kunisue, T., Tao, L., Kannan, K., Subramanian, An., Tanabe, S. and Iwata, H. (2010):
    Dioxin-like and perfluorinated compounds in pigs in an Indian openwaste dumping site: toxicokinetics and effects on hepatic cytochrome P450 and blood plasma hormones,
    Environmental Toxicology and Chemistry, 29(7), 1551-1560.
  6. Kubota, A., Watanabe, M., Kunisue, T., Kim, E. Y., Tanabe, S. and Iwata, H. (2010):
    Hepatic CYP1A introduction by chlorinated dioxins and related compounds in the endangered black-footed albatross from the North Pacific,
    Environmental Science & Technology, 44(9), 3559-3565.
  7. Iwata, H., Nagahama, N., Kim, E. Y., Watanabe, M. X. and Sudo, A. (2010):
    Effects of in ovo exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic AHR/ARNT-CYP1A signaling pathways in common cormorants (Phalacrocoraxcarbo),
    Comparative Biochemistry and Physiology, Part C, 152(2), 224-231.
  8. Agusa, T., Kunoto, T., Kubota, R., Inoue, S., Fujihara, J., Minh, T. B., Ha, N. N., Tu, N. P. C., Trang, P. T. K., Chamnan, C., Takeshita, H., Iwata, H., Tuyen, B. C., Viet, P. H., Tana, T. S. and Tanabe, S. (2010):
    Exposure, metabolism, and health effects of arsenic in residents from arsenic-contaminated groundwater areas of Vietnam and Cambodia: A review,
    Reviews on Environmental Health, 25(3), 193-220.
  9. Nakayama, K., Handoh, I. C., Kitamura, S., Kim, E. Y., Iwata, H. and Tanabe, S. (2010):
    A microarray data analysis method to evaluate the impact of contaminants on wild animals,
    Science of the Total Environment, 408(23), 5824-5827.
  10. Tanaka, Y., Komori, H., Mori, S., Soga, Y., Tsubaki, T., Terada, M., Miyazaki, T., Fujino, T., Nakamura, S., Kanno, H., Sawasaki, T., Endo, Y. and Nose, M.(2010):
    Evaluating the role of rheumatoid factors in the development of rheumatoidarthritis in a mouse model with a newly established ELISA system,
    The Tohoku Journal of Experimental Medicine, 220, 199-206.
  11. Matsuoka, K., Komori, H., Nose, M., Endo, Y.and Sawasaki, T. (2010):
    Simple screening method for autoantigen proteins using the N-terminal biotinylated protein library produced by wheat cell-free synthesis,
    Journal of Proteome Research, 9(8), 4264-4273.
  12. Furukawa, H., Tohma, S., Kitazawa, H., Komori, H., Nose, M. and Ono, M. (2010):
    Role of SLAM-associated protein in the pathogenesis of autoimmune diseases and immunological disorders.,
    ArchivumImmunologiae et TherapiaExperimentalis, 58(1), 37-44.
  13. Mizuki, S., Oishi, H., Zhang, M. C., Kamogawa, J., Miyazaki, T., Ono, M., Takahashi, S., Yamamoto, H. and Nose, M. (2010):
    Genetic heterogeneity in rheumatoid arthritis mouse models induced by extrinsic and intrinsic factors,
    Pathology International, 60(6), 430-437.
  14. Kim, J. W., Ishibashi, H., Hirano, M., Jang, H. S., Kim, J. G., Takao, Y., Ichikawa, N., Shinohara, R. and Arizono, K. (2010):
    Contamination of pharmaceutical and personal care products in sewage treatment plants and surface waters in South Korea and their removal during activated sludge treatment,
    Japan Journal of Environmental Chemistry, 20(2), 127-136.
  15. Kai, H., Ishibashi, Y., Mori, T., Ishibashi, H., Kawaguchi, T., Ohwaki, H., Arizono, K. and Takemasa, T. (2010):
    Decolorization and estrogenic activity of colored livestock watewater by electrolysis system,
    Material Recycle and Waste Management Research, 12, 128-135.
  16. Suzuki, K.,Kashiwagi, K., Ujihara, M., Marukane, T., Tazaki, A., Watanabe, K., Mizuno, N., Ueda, Y., Kondoh, H., Kashiwagi, A. and Mochii, M. (2010):
    Characterization of a novel type I keratin gene and generation of transgenic lines with fluorescent reporter genes driven by its promoter/enhancer in Xenopuslaevis,
    Developmental Dynamics, 12(3), 3172-3181.
  17. 阿草哲郎・藤原純子・竹下治男・田辺信介・岩田久人・國頭 恭 (2010):
    ベトナム人におけるAS3MT遺伝子多型とヒ素代謝能の関係,
    DNA多型, 18(1), 242-245.
  18. 川添禎浩・那智和奈・石橋弘志・小原智未・有薗幸司・橋本香織・北条康司・鈴木 隆 (2010):
    ダイエタリーサプリメント使用される大豆抽出物とエチニルエストラジオールの複合エストロゲン活性,
    食品衛生学雑誌, 51(3), 101-109.

学会発表：国際学会

  1. Iwata, H., Lee, J. S., Kim, E. Y. and Nomaru, K. (2011):
    Molecular and functional characterization of aryl hydrocarbon receptor repressor (AHRR) from the chicken (Gallus gallus),
    Society of Toxicology 50thAnniversary Annual Meeting,
    Wasihngton, D.C., USA, March, Program, 75.
  2. Agusa, T., Kunito, T., Fujiwara, J., Takeshita, T. B., Min, P. K., Viet, P. H., Tanabe, S. and Iwata, H. (2011):
    Association of arsenic exposure and genetic polymorphisms with arsenic metabolism in a Vietnamese population,
    Society of Toxicology 50thAnniversary Annual Meeting,
    Washington, D.C., USA, March, Program, 423.
  3. Teraoka, H., Ito, S., Ukai, N., Kim, E. Y., Iwata, H., Kitazawa, T., Hiraga, T. and Endoh, D. (2011):
    2,3,7,8-tetrachlorodibenzo-p-dioxin responsive transcripts in avian embryonic liver, identified by large-scale differential display system with vertebrate-common degenerate oligonucleotide primers,
    Society of Toxicology 50thAnniversary Annual Meeting,
    Washington D.C., USA, March, Program, 362.
  4. Agusa, T., Fujihara, J., Takeshita, H., Tanabe, S., Iwata, H., Kunito, T., Minh, T. B., Trang, P. T. K. and Viet, P. H. (2010):
    Methylation of inorganic arsenic and genetic polymorphisms in arsenic (+III oxidation state) methyltransferase in a Vietnamese population,
    The 3rd International Congress on Arsenic in the Environment,
    Tainan, Taiwan, May, Proceedings, 329-331.
  5. Agusa, T., Nomura, K., Kunito, T., Anan, Y., Iwata, H. and Tanabe, S. (2010):
    Accumulation of trace elements in harp seals (Phocagroenlandica) from Pangnirtung in Baffin Island, Canada,
    6th International Conference on Marine Pollution and Ecotoxicology,
    Hong Kong, China, May, Abstracts, P-28.
  6. Kamao, T., Miyazaki, T., Soga, Y., Komori, H., Terada, M. and Nose, M. (2010):
    Common and different gene loci susceptible to sialoadenitis and dacryoadenitis in a sjogren's syndrome mouse model,
    14th International Congress of Immunology,
    Kobe, Japan, August.
  7. Tanaka, Y., Fujino, T., Terada, M., Ito, M., Shudo, M., Okabe, M. And Nose, M. (2010):
    A novel mouse model for primary focal segmental glomerulosclerosis developing associated with insertional mutagenesis by transgene,
    14th International Congress of Immunology,
    Kobe, Japan, August.
  8. Miyazaki, T., Tanaka, Y., Kurata, M., Ono, M. and Nose, M. (2010):
    Allelic polymorphism of murine osteopontin implicates functional differences in antigen presentation by dendritic cells,
    14th International Congress of Immunology,
    Kobe, Japan, August.
  9. Ishibashi, H., Kim, E. Y. and Iwata, H. (2010):
    Transcriptional activities of Baikal seal (Pusasibirica) peroxisome proliferator-activated receptor α by perfluoroalkyl carboxylates and perfluoroalkylsulfonates,
    International Symposium on Modeling and Analysis of Marine Environmental Problems (MAMEP 2010),
    Matsuyama, Japan, September, Abstract, 54.
  10. Suzuki, K. T. and Iwata, H. (2010):
    Identification and characterization of CYP1 genes in Xenopuslaevis and Xenopustropicalis,
    International Symposium on Modeling and Analysis of Marine Environmental Problems (MAMEP 2010),
    Matsuyama, Japan, September, Abstract, 61.
  11. Hirano, M., Ishibashi, H., Kim, E. Y., Arizono, K. and Iwata, H. (2010):
    Effects of endogenous and xenobiotic ligands on DNA binding and transactivation of the mysidecdysteroid receptor,
    International Symposium on Modeling and Analysis of Marine Environmental Problems (MAMEP 2010),
    Matsuyama, Japan, September, Abstract, 62.
  12. Thuruthippallil L. M., Kim, E. Y. and Iwata, H.(2010):
    Risk assessment of dioxins and related compounds in the black-footed albatross: Application of an in vitro approach,
    International Symposium on Modeling and Analysis of Marine Environmental Problems (MAMEP 2010),
    Matsuyama, Japan, September, Abstract, 78.
  13. Iwata, H., Kim, E. Y., Lee, J. S. and Kubota, A. (2010):
    Regulation and catalytic function of avian CYP1A: Interspecies similarities and differences. 10th International Symposium on Cytochrome P450 Biodiversity and Biotechnology,
    Woods Hole, USA, October, Abstracts, 9D.
  14. Hirano, M., Ishibashi, H., Kim, E., Arizono, K. and Iwata, H. (2010):
    Functional analyses of the mysidecdysteroid receptor: molecular cloning, DNA binding ability and ligand-induced transactivation,
    10th International Symposium on Cytochrome P450 Biodiversity and Biotechnology,
    Woods Hole, USA, October, Abstracts, 215B.
  15. Ishibashi, H., Kim, E. Y. and Iwata, H. (2010):
    Transactivation potencies of Baikal seal (Pusasibirica) peroxisome proliferator-activated receptor α by perfluoroalkyl carboxylates and perfluoroalkylsulfonates,
    10th International Symposium on Cytochrome P450 Biodiversity and Biotechnology,
    Woods Hole, USA, October, Abstracts, 216B.
  16. Kubota, A., Stegeman, J., Goldstone, J., Nelson, D., Kim, E. Y., Tanabe, S. and Iwata, H. (2010):
    Cytochrome P450 CYP2 genes in the common cormorant: evolutionary relationships with diapsid CYP2 clan sequences and chemical effects on their expression,
    10th International Symposium on Cytochrome P450 Biodiversity and Biotechnology,
    Woods Hole, USA, Abstracts, 218B.
  17. Suzuki, K. and Iwata, H. (2010):
    Characterization of CYP1 genes in Xenopuslaevis and Xenopustropicalis,
    10th International Symposium on Cytochrome P450 Biodiversity and Biotechnology,
    Woods Hole, USA, October, Abstracts, 219B.
  18. Iwata, H. (2010):
    Studies on cytochrome P450 expression and function in wildlife,
    NUTMEG 2010 - 28th Annual Meeting,
    Woods Hole USA, Program, 2.
  19. Iwata, H. and Kim, E. Y. (2010):
    Chemical impacts on aquatic birds and mammals: xenobiotic receptor-based risk assessment, The 4th Bilateral Seminar Italy-Japan, Physical and Chemical Impacts on Marine Organisms - For Conservation of Biodiversity and Sustainability,
    Nagakute, Japan, October, Abstract, 9.
  20. Yamaguchi, K., Kim, E. Y., Kubota, A. and Iwata, H. (2010):
    Functional characterization of cytochrome P450 1A1, 1A2 and 1B1 from the Baikal seal (Pusasibirica),
    韓国環境分析学会秋季学術大会 & The 2nd Korea-Japan Symposium on Environmental Chemistry,
    Seoul, Korea, November, Abstracts, 124.

学会発表：国内学会

  1. 阿草哲郎・岩田久人・國頭 恭・藤原純子・Minh, T. B.・Trang, P. T. K.・Viet, P. H.・竹下治男・田辺信介　(2011):
    ベトナム人におけるヒ素代謝能の個人差：ヒ素曝露レベルと代謝遺伝子多型の影響,
    第１６回ヒ素シンポジウム,
    旭川市, ２月, 講演要旨集, 48．
  2. 能勢眞人 (2011): 膠原病のポリジーンネットワーク,
    愛媛大学プロテオ医学研究センター　第１回学術シンポジウム　難病のプロテオゲノミクス,
    松山市,２月.
  3. 阿草哲郎・岩田久人・藤原純子・國頭恭・Minh, T. B.・Trang, P. T. K.・Viet, P. H.・竹下治男・田辺信介 (2010):
    ベトナム人のヒ素代謝プロファイルとGST遺伝子多型の関係：ヒ素暴露レベルの影響.第19回環境化学討論会,
    春日井市, ６月, 講演要旨集, 236-237.
  4. 阿草哲郎・岩田久人・藤原純子・國頭恭・竹下治男・Minh, T. B.・Trang, P. T. K.・Viet, P. H.・田辺信介(2010):
    ベトナムのヒ素汚染地域住民におけるヒ素代謝に関与する要因,
    第21回日本微量元素学会,
    京都市, ７月, プログラム・抄録集, 137.
  5. 藤澤希望・池中良徳・山本秀明・金恩英・李鎮善・岩田久人・石塚真由美 (2010):
    芳香族炭化水素受容体(AhR)の分子生物学的解析による鳥類のダイオキシン類感受性評価,
    第61回北海道獣医師大会・平成22年度北海道地区三学会, 函館市, ９月.
  6. 山内良子・石橋弘志・内田雅也・孫?富・平野将司・金俊佑・冨永伸明・有薗幸司 (2010):
    ふっ素テロマーアルコールがヒメダカ再生産に及ぼす影響, 第16回バイオアッセイ研究会・日本環境毒性学会, つくば市, ９月.
  7. Suzuki, T. K. and Iwata, H.(2010):
    Transcriptional regulation of CYP1A genes in amphibians,
    環境ホルモン学会（日本内分泌撹乱化学物質学会）第13回研究発表会,
    東京, １２月, 要旨集, 48.
  8. Hirano, M., Ishibashi, H., Kim, E. Y., Arizono, K. and Iwata, H. (2010):
    Effects of endogenous and xenobiotic compounds on DNA binding and transactivation of the crustacean ecdysteroid receptor,
    環境ホルモン学会（日本内分泌撹乱化学物質学会）第13回研究発表会,
    東京, １２月, 要旨集, 61.
  9. Ishibashi, H., Kim, E. Y. and Iwata, H. (2010):
    Transactivation potencies of the Baikal Seal (Pusasibirica) peroxisome proliferator-activated receptor α by perfluoroalkyl carboxylates and sulfonates: Estimation of PFOA induction equivalency factors,
    環境ホルモン学会（日本内分泌撹乱化学物質学会）第13回研究発表会, 東京, １２月, 要旨集, 62.
  10. Iwata, H., Lee, J. S. and Kim, E. Y. (2010):
    Characterization of the AHR/ARNT/AHRR-CYP1A signaling pathway in avian species,
    環境ホルモン学会（日本内分泌撹乱化学物質学会）第13回研究発表会,
    東京, １２月, 要旨集, 63.
  11. Pham, T. T. L., Ishibashi, H., Kadota, M., Kim, E. Y. and Iwata, H. (2010):
    Transactivation potencies of the Baikal seal (Pusasibirica) pregnane X receptor by persistent organic pollutants,
    環境ホルモン学会（日本内分泌撹乱化学物質学会）第13回研究発表会,
    東京, １２月, 要旨集, 114.
  12. Pham, T. D., Ishibashi, H., Kim, E. Y. and Iwata, H. (2010):
    Screening of environmental chemicals using a surface plasmon resonance (SPR) biosensor in combination with constitutive androstane receptor (CAR).
    環境ホルモン学会（日本内分泌撹乱化学物質学会）第13回研究発表会,
    東京, １２月, 要旨集, 115.